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引用和文献 (32)
Invitrogen™
4,4-二氟-5,7-二甲基-4-硼-3a,4a-二氮杂-s-茚并三-3-十二烷酸酯 (CholEsteryl BODIPY™ FL C12)
胆固醇酯是胆固醇 3β-羟基脂肪酸酯化的产物。这类极具非极性的物质是动脉粥样硬化斑块和低/高密度脂蛋白（LDL 和 HDL）核心的主要脂质成分。在荧光显微镜下，发绿色荧光的 BODIPY™ FL了解更多信息
| 货号 | 数量 |
|---|---|
| C3927MP | 1 mg |
货号 C3927MP
价格（CNY)
3,948.00
Each
数量:
1 mg
价格（CNY)
3,948.00
Each
胆固醇酯是胆固醇 3β-羟基脂肪酸酯化的产物。这类极具非极性的物质是动脉粥样硬化斑块和低/高密度脂蛋白（LDL 和 HDL）核心的主要脂质成分。在荧光显微镜下，发绿色荧光的 BODIPY™ FL C12 胆固醇酯可用作观察胆固醇运输和受体介导脂蛋白内吞的示踪剂，同时可用作一种通用非交换型膜标记物。
仅供科研使用。不可用于诊断程序。
规格
化学名称或材料胆固醇类似物
建议的储存条件在冷冻冰箱（-5 至 -30°C）中避光储存。
物理形态Solid
产品线BODIPY
数量1 mg
Unit SizeEach
常见问题解答 (FAQ)
How should I store CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP) once reconstituted?
What is the molecular weight of CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP)? Is the molecular weight based on the cholesteryl moiety together with BODIPY?
How do I reconstitute CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP)?
引用和文献 (32)
引用和文献
Abstract
Streptococcal serum opacity factor increases the rate of hepatocyte uptake of human plasma high-density lipoprotein cholesterol.
Journal:Biochemistry
PubMed ID:20879789
Serum opacity factor (SOF), a virulence determinant of Streptococcus pyogenes, converts plasma high-density lipoproteins (HDL) to three distinct species: lipid-free apolipoprotein (apo) A-I, neo HDL, a small discoidal HDL-like particle, and a large cholesteryl ester-rich microemulsion (CERM) that contains the cholesterol esters (CE) of up to ~400000 HDL particles and
Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.
Journal:J Clin Endocrinol Metab
PubMed ID:9506760
This study examines the ability of human high density lipoproteins (HDL3) to deliver cholesteryl esters to human granulosa cells and describes the selective cholesterol pathway by which this occurs. Luteinized cells obtained from subjects undergoing in vitro fertilization-embryo transfer procedures were incubated with native HDL3 (or radiolabeled or fluorescently labeled
High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion.
Journal:J Biol Chem
PubMed ID:11301333
'High density lipoprotein (HDL) mediates reverse transport of cholesterol from atheroma foam cells to the liver, but the mechanisms of hepatic uptake and trafficking of HDL particles are poorly understood. In contrast to its accepted role as a cell surface receptor, scavenger receptor class B type 1 (SR-BI) is shown
Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway.
Journal:J Biol Chem
PubMed ID:7499399
'The metabolism of chylomicron remnants in mice deficient in low density lipoprotein receptor (LDLr) or apolipoprotein E (apoE) was compared with that of control C57BL/6J mice. Mice were injected intravenously with chylomicron-like emulsions labeled with radioactive lipids. Blood samples were taken at fixed time intervals from the retro-orbital sinus, and
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery : roles of VLDL and HDL.
Journal:Circ Res
PubMed ID:10764410
'The major goal of this study was to determine the interactions of VLDL surface and core lipids with the artery wall. We first demonstrated in vitro that surface lipid in VLDL could be traced using the phospholipid-like fluorescent probe 1,1''-dioctadecyl-3,3, 3'',3''-tetramethyl-indocarbocyanine (DiI). The core of VLDL particles was traced by