Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism.
AuthorsTai CC, Chen CY, Lee HS, Wang YC, Li TK, Mersamm HJ, Ding ST, Wang PH,
JournalJ Biol Chem
PubMed ID19755416
'Serum amyloid A (SAA) reduces fat deposition in adipocytes and hepatoma cells. Human SAA1 mRNA is increased by docosahexaenoic acid (DHA) treatment in human cells. These studies asked whether DHA decreases fat deposition through SAA1 and explored the mechanisms involved. We demonstrated that DHA increased human SAA1 and C/EBPbeta mRNA ... More