Decreased interferon-a and interferon-ß production in obesity and expression of suppressor of cytokine signaling.
AuthorsTeran-Cabanillas E, Montalvo-Corral M, Caire-Juvera G, Moya-Camarena SY, Hernández J,
JournalNutrition
PubMed ID22951153
We analyzed the interferon-a (IFN-a), IFN-ß, and proinflammatory responses induced by Toll-like receptor (TLR) ligands in peripheral blood mononuclear cells (PBMCs) from obese subjects and their association with suppressor of cytokine signaling-1 (SOCS1) and SOCS3 expression. The IFN responses were measured by real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) ... More