Leishmania braziliensis amastigotes stimulate production of IL-1ß, IL-6, IL-10 and TGF-ß by peripheral blood mononuclear cells from nonendemic area healthy residents.
AuthorsGomes CM, Avila LR, Pinto SA, Duarte FB, Pereira LI, Abrahamsohn IA, Dorta ML, Vieira LQ, Ribeiro-Dias F, Oliveira MA,
Journal
PubMed ID24575815
'Leishmania (Viannia) braziliensis causes cutaneous and mucosal leishmaniasis in several countries in Latin America. In mammals, the parasites live as amastigotes, interacting with host immune cells and stimulating cytokine production that will drive the type of the specific immune responses. Generation of Th17 lymphocytes is associated with tissue destruction and ... More