Competitive inhibition by NAG-1/GDF-15 NLS peptide enhances its anti-cancer activity.
Authors:Lee J, Kim I, Yoo E, Baek SJ,
Journal:Biochem Biophys Res Commun
PubMed ID:31474335
Non-steroidal anti-inflammatory drug activated gene-1 (NAG-1), also known as growth differentiation factor 15 (GDF15), is a TGF-ß (transforming growth factor beta) superfamily protein with a distinctive secretion pathway. NAG-1 is associated with multiple diseases including cancer, wherein it plays a role in both pro- and anti-cancer activities. We previously reported ... More