Cationic gradient reversal and cytoskeleton-independent volume regulatory pathways define an early stage of apoptosis.
Authors:Bortner CD, Sifre MI, Cidlowski JA,
Journal:J Biol Chem
PubMed ID:18187415
'Cell shrinkage, or apoptotic volume decrease (AVD), is a ubiquitous characteristic of programmed cell death that is independent of the death stimulus and occurs in all examples of apoptosis. Here we distinguished two specific stages of AVD based on cell size and a unique early reversal of intracellular ions that ... More