Structure and composition of aggregates in two large European rivers, based on confocal laser scanning microscopy and image and statistical analyses.
AuthorsLuef B, Neu TR, Zweimüller I, Peduzzi P,
JournalAppl Environ Microbiol
PubMed ID19633114
Floating riverine aggregates are composed of a complex mixture of inorganic and organic components from their respective aquatic habitats. Their architecture and integrity are supplemented by the presence of extracellular polymeric substances of microbial origin. They are also a habitat for virus-like particles, bacteria, archaea, fungi, algae, and protozoa. In ... More
Inositol 1,4,5-trisphosphate-dependent oscillations of luminal [Ca2+] in permeabilized HSY cells.
AuthorsTanimura A, Turner RJ
JournalJ Biol Chem
PubMed ID8940075
Oscillations in intracellular Ca2+ concentration ([Ca2+]i) are thought to play an important role in phosphoinositide-linked Ca2+ signaling events. We demonstrate corresponding inositol 1,4, 5-trisphosphate (IP3)-dependent oscillations of Ca2+ concentration within the lumen of the IP3-sensitive stores ([Ca2+]L) of saponin-permeabilized HSY cells by monitoring [Ca2+]L with the fluorescent Ca2+ indicator Mag-fura-2. ... More
Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells.
AuthorsWüstner D, Mondal M, Huang A, Maxfield FR
JournalJ Lipid Res
PubMed ID14679167
We analyzed the intracellular transport of HDL and its associated free sterol in polarized human hepatoma HepG2 cells. Using pulse-chase protocols, we demonstrated that HDL labeled with Alexa 488 at the apolipoprotein (Alexa 488-HDL) was internalized by a scavenger receptor class B type I (SR-BI)-dependent process at the basolateral membrane ... More
Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis.
Authors
JournalElife
PubMed ID27623009
miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110.
Authors
JournalNature
PubMed ID24899310
TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer.
Authors
JournalCarcinogenesis
PubMed ID31621840
Thinned-skull cranial window technique for long-term imaging of the cortex in live mice.
Authors
JournalNat Protoc
PubMed ID20134419
Quantitative third-harmonic generation imaging of mouse visual cortex areas reveals correlations between functional maps and structural substrates.
Authors
JournalBiomed Opt Express
PubMed ID33149977
NGF steers microglia toward a neuroprotective phenotype.
Authors
JournalGlia
PubMed ID29473218
Klf4 has an unexpected protective role in perivascular cells within the microvasculature.
Authors
JournalAm J Physiol Heart Circ Physiol
PubMed ID29631369
DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling.
Authors
JournalDevelopment
PubMed ID35502759
Deletion of Vhl in Dmp1-Expressing Cells Causes Microenvironmental Impairment of B Cell Lymphopoiesis.
Authors
JournalFront Immunol
PubMed ID35250971
Macrophages Use Distinct Actin Regulators to Switch Engulfment Strategies and Ensure Phagocytic Plasticity In Vivo.