A microplate reader-based nonisotopic histone deacetylase activity assay.
AuthorsHeltweg B, Jung M
JournalAnal Biochem
PubMed ID11878795
'Recent years have brought an enormous increase in knowledge concerning the involvement of histone deacetylase (HDAC) in gene regulation and the potential use of its inhibitors in transcription therapy. This also stimulates research toward new methods for the determination of HDAC activity and thus the potency of potential inhibitors. We ... More