Heterogeneous nuclear ribonucleoprotein (hnRNP) E1 binds to hnRNP A2 and inhibits translation of A2 response element mRNAs.
AuthorsKosturko LD, Maggipinto MJ, Korza G, Lee JW, Carson JH, Barbarese E
JournalMol Biol Cell
PubMed ID16775011
'Heterogeneous nuclear ribonucleoprotein (hnRNP) A2 is a trans-acting RNA-binding protein that mediates trafficking of RNAs containing the cis-acting A2 response element (A2RE). Previous work has shown that A2RE RNAs are transported to myelin in oligodendrocytes and to dendrites in neurons. hnRNP E1 is an RNA-binding protein that regulates translation of ... More
Evolutionary origins for social vocalization in a vertebrate hindbrain-spinal compartment.
AuthorsBass AH, Gilland EH, Baker R,
JournalScience
PubMed ID18635807
'The macroevolutionary events leading to neural innovations for social communication, such as vocalization, are essentially unexplored. Many fish vocalize during female courtship and territorial defense, as do amphibians, birds, and mammals. Here, we map the neural circuitry for vocalization in larval fish and show that the vocal network develops in ... More
Location of bladder and urethral sphincter motoneurons in the male guinea pig (Cavia porcellus).
AuthorsKuipers R, Izhar Z, Gerrits PO, Miner W, Holstege G
JournalNeurosci Lett
PubMed ID15147780
Although the guinea pig is used widely in experimental medical research, including in studies on micturition control, the spinal origin of preganglionic parasympathetic bladder and somatic external urethral sphincter motoneurons is not known. In the male guinea pig using wheat germ agglutinin-conjugated horseradish peroxidase and dextran Alexa Fluor 488/568 tracers, ... More
Glycolipid trafficking in Drosophila undergoes pathway switching in response to aberrant cholesterol levels.
AuthorsHortsch R, Lee E, Erathodiyil N, Hebbar S, Steinert S, Lee JY, Chua DS, Kraut R,
JournalMol Biol Cell
PubMed ID20053687
In lipid storage diseases, the intracellular trafficking of sphingolipids is altered by conditions of aberrant cholesterol accumulation. Drosophila has been used recently to model lipid storage diseases, but the effects of sterol accumulation on sphingolipid trafficking are not known in the fly, and the trafficking of sphingolipids in general has ... More
Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans.
AuthorsWard ES, Zhou J, Ghetie V, Ober RJ
JournalInt Immunol
PubMed ID12578848
IgG is the most abundant serum antibody and is an essential component of the humoral immune response. It is known that the 'neonatal' Fc receptor (FcRn) plays a role in maintaining constant serum IgG levels by acting as a protective receptor which binds and salvages IgG from degradation. However, the ... More
Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling.
Authors
JournalMol Syst Biol
PubMed ID31777174
Postnatal development of retrosplenial projections to the parahippocampal region of the rat.
Authors
JournalElife
PubMed ID27008178
In vitro formation of neuroclusters in microfluidic devices and cell migration as a function of stromal-derived growth factor 1 gradients.
Authors
JournalCell Adh Migr
PubMed ID26744909
Dynamics of BMP signaling and distribution during zebrafish dorsal-ventral patterning.
Authors
JournalElife
PubMed ID28857744
Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification.
Authors
JournalEur J Neurosci
PubMed ID23773064
Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos.
Authors
JournalJ Cell Sci
PubMed ID28827407
Architecture and organization of mouse posterior parietal cortex relative to extrastriate areas.
Authors
JournalEur J Neurosci
PubMed ID30456892
SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages.
Authors
JournalAutophagy
PubMed ID27929705
Fate restriction and multipotency in retinal stem cells.
Authors
JournalCell Stem Cell
PubMed ID22136930
Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs.