β-BODIPY™ FL C12-HPC(2-(4,4-二氟-5,7-二甲基-4-硼杂-3a,4a-二氮杂-s-引达省-3-月桂酰基)-1-二十六烷酰基-sn甘油-3-磷酸乙醇胺)
&beta;-BODIPY&trade; FL C<sub>12</sub>-HPC(2-(4,4-二氟-5,7-二甲基-4-硼杂-3a,4a-二氮杂-<i>s</i>-引达省-3-月桂酰基)-1-二十六烷酰基-<i>sn</i>甘油-3-磷酸乙醇胺)
Invitrogen™

β-BODIPY™ FL C12-HPC(2-(4,4-二氟-5,7-二甲基-4-硼杂-3a,4a-二氮杂-s-引达省-3-月桂酰基)-1-二十六烷酰基-sn甘油-3-磷酸乙醇胺)

发明亮荧光的 BODIPY(4,4-二氟-3a,4a-二氮杂-®s-引达省)荧光基团的本质是亲脂性的,与大多数其他长波长染料不同。因此,掺入这些荧光基团的探针更可能模拟天然脂质的性质。BODIPY® 脂肪酸类似物(如 BODIPY® 500/510了解更多信息
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货号数量
D3792100 μg
货号 D3792
价格(CNY)
2,364.00
Each
添加至购物车
数量:
100 μg
价格(CNY)
2,364.00
Each
添加至购物车
发明亮荧光的 BODIPY(4,4-二氟-3a,4a-二氮杂-®s-引达省)荧光基团的本质是亲脂性的,与大多数其他长波长染料不同。因此,掺入这些荧光基团的探针更可能模拟天然脂质的性质。BODIPY® 脂肪酸类似物(如 BODIPY® 500/510 十二烷基诺酸 (D-3823) 和 BODIPY FL 十二烷基二甲酸 (D-3822) )在细胞中会发生类天然运输和代谢。因此,它们是对脂质运输活动的有效示踪剂,同时也是非常有用的通用型膜探针。
仅供科研使用。不可用于诊断程序。
规格
化学名称或材料磷脂
建议的储存条件在冷冻冰箱(-5 至 -30°C)中避光储存。
物理形态Solid
产品线BODIPY
数量100 μg
Unit SizeEach

引用和文献 (31)

引用和文献
Abstract
Separation and characterization of late endosomal membrane domains.
Authors:Kobayashi T, Beuchat MH, Chevallier J, Makino A, Mayran N, Escola JM, Lebrand C, Cosson P, Kobayashi T, Gruenberg J
Journal:J Biol Chem
PubMed ID:12065580
'Very little is known about the biophysical properties and the lipid or protein composition of membrane domains presumably present in endocytic and biosynthetic organelles. Here we analyzed the membrane composition of late endosomes by suborganellar fractionation in the absence of detergent. We found that the internal membranes of this multivesicular ... More
Multidrug transporter activity in lymphocytes.
Authors:Elliott JI, Raguz S, Higgins CF,
Journal:Br J Pharmacol
PubMed ID:15492020
'Multidrug transporters play a dual role in haematopoietic cells, mediating the efflux of xenobiotics and regulating cell migration. For several reasons including the lack of specific antibodies, reports of multidrug transporter distribution on lymphocytes conflict. Murine B cells have been reported to completely lack transporter activity. Through analysis of parental ... More
gamma-cyclodextrins greatly enhance translocation of hydrophobic fluorescent phospholipids from vesicles to cells in culture. Importance of molecular hydrophobicity in phospholipid trafficking studies.
Authors:Tanhuanpää K, Somerharju P
Journal:J Biol Chem
PubMed ID:10585403
'Short-chain, fluorescent derivatives are commonly used to investigate intracellular phospholipid trafficking. However, their use can yield misleading results because they, unlike the native species, can rapidly distribute between organelles due to their low hydrophobicity. On the other hand, hydrophobic derivatives are very difficult to introduce to cells and thus have ... More
Fluorescent membrane probes incorporating dipyrrometheneboron difluoride fluorophores.
Authors:Johnson ID, Kang HC, Haugland RP
Journal:Anal Biochem
PubMed ID:1799206
'The spectroscopic properties of a new series of fatty acid analogs in which a dipyrrometheneboron difluoride fluorophore forms a segment of the acyl methylene chain are presented and their characteristics as fluorescent membrane probes are examined. When incorporated as a low mole fraction component in model phospholipid membranes, the probes ... More
Intracellular surfactant removal from phagocytized minerals: development of a fluorescent method using a BODIPY-labeled phospholipid.
Authors:Das AR, Cilento EV, Keane MJ, Wallace WE
Journal:Inhal Toxicol
PubMed ID:10880156
'Lung surfactant serves as a protective coating when adsorbed on particle surfaces, so its removal or rate of removal in vivo may affect expression of mineral cytotoxicity. Removal of phospholipid surfactant components from the surface of mineral particles ingested by alveolar macrophages (AM) was measured using fluorescence microscopy. Dipalmitoylphosphatidylcholine with ... More