Synthesis of novel fluorinated coumarins: excellent UV-light excitable fluorescent dyes.
Authors:Sun WC, Gee KR, Haugland RP
Journal:Bioorg Med Chem Lett
PubMed ID:9873685
'Two new fluorinated fluorescent dyes, 6,8-difluoro-7-hydroxy-4-methylcoumarin (Marina Blue) and 3-carboxy-6,8-difluoro-7-hydroxycoumarin (Pacific Blue), exhibit excellent photophysical properties among a series of novel fluorinated 7-hydroxycoumarins. Most of these fluorinated coumarins have quantum yields (0.63 to 0.89) equal to or higher than that of the parent compound (0.63), which, in combination with their ... More