Diverse cell types and parallel pathways are characteristic of the vertebrate nervous system, yet it remains a challenge to define the basic components of most neural structures. We describe a process termed retrograde photodynamics that allowed us to rapidly make the link between morphology, physiology, and connectivity for ganglion cells ... More
Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos.
AuthorsKizhatil K, Davis JQ, Davis L, Hoffman J, Hogan BL, Bennett V,
JournalJ Biol Chem
PubMed ID17620337
E-cadherin is a ubiquitous component of lateral membranes in epithelial tissues and is required to form the first lateral membrane domains in development. Here, we identify ankyrin-G as a molecular partner of E-cadherin and demonstrate that ankyrin-G and beta-2-spectrin are required for accumulation of E-cadherin at the lateral membrane in ... More
Detection of a glycosylation-dependent ligand for the T lymphocyte cell adhesion molecule CD2 using a novel multimeric recombinant CD2-binding assay.
The CD2 molecule plays an important role in T cell adhesion by interacting with the ligands CD58 (LFA-3) and CD59. In order to detect additional ligands for CD2, potentially of low binding affinity, we have prepared a highly fluorescent, multimeric form of rCD2 whose binding to cells can be quantified ... More
Glioblastoma: a pathogenic crosstalk between tumor cells and pericytes.
Authors
JournalPLoS One
PubMed ID25032689
Single vs. Combined Therapeutic Approaches in Rats With Chronic Spinal Cord Injury.