BODIPY™ FL C12-鞘磷脂（N-(4,4-二氟-5,7-二甲基-4-硼-3a,4a-二氮杂-s-引达省-3-十二酰基)鞘氨醇磷酸胆碱蓝）
BODIPY&trade; FL C<sub>12</sub>-鞘磷脂（<i>N</i>-(4,4-二氟-5,7-二甲基-4-硼-3a,4a-二氮杂-<i>s</i>-引达省-3-十二酰基)鞘氨醇磷酸胆碱蓝）
引用和文献 (24)
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BODIPY™ FL C12-鞘磷脂（N-(4,4-二氟-5,7-二甲基-4-硼-3a,4a-二氮杂-s-引达省-3-十二酰基)鞘氨醇磷酸胆碱蓝）

绿色荧光鞘磷脂 BODIPY™ FL C12-鞘磷脂可用于研究鞘脂类在细胞中的转运和信号转导通路。了解更多信息
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货号数量
D7711250 μL
货号 D7711
价格（CNY)
5,717.00
Each
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数量:
250 μL
价格（CNY)
5,717.00
Each
添加至购物车
绿色荧光鞘磷脂 BODIPY™ FL C12-鞘磷脂可用于研究鞘脂类在细胞中的转运和信号转导通路。
仅供科研使用。不可用于诊断程序。
规格
化学名称或材料Sphingolipids
建议的储存条件在冷冻冰箱（-5 至 -30°C）中避光储存。
产品线BODIPY
数量250 μL
Unit SizeEach

引用和文献 (24)

引用和文献
Abstract
Fluorescence-based selection of gene-corrected hematopoietic stem and progenitor cells from acid sphingomyelinase-deficient mice: implications for Niemann-Pick disease gene therapy and the development of improved stem cell gene transfer procedures.
Authors:Erlich S, Miranda SR, Visser JW, Dagan A, Gatt S, Schuchman EH
Journal:Blood
PubMed ID:9864149
'The general utility of a novel, fluorescence-based procedure for assessing gene transfer and expression has been demonstrated using hematopoietic stem and progenitor cells. Lineage-depleted hematopoietic cells were isolated from the bone marrow or fetal livers of acid sphingomyelinase-deficient mice, and retrovirally transduced with amphotropic or ecotropic vectors encoding a normal ... More
gamma-cyclodextrins greatly enhance translocation of hydrophobic fluorescent phospholipids from vesicles to cells in culture. Importance of molecular hydrophobicity in phospholipid trafficking studies.
Authors:Tanhuanpää K, Somerharju P
Journal:J Biol Chem
PubMed ID:10585403
'Short-chain, fluorescent derivatives are commonly used to investigate intracellular phospholipid trafficking. However, their use can yield misleading results because they, unlike the native species, can rapidly distribute between organelles due to their low hydrophobicity. On the other hand, hydrophobic derivatives are very difficult to introduce to cells and thus have ... More
A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways.
Authors:Steinert S, Lee E, Tresset G, Zhang D, Hortsch R, Wetzel R, Hebbar S, Sundram JR, Kesavapany S, Boschke E, Kraut R,
Journal:PLoS ONE
PubMed ID:18716682
'BACKGROUND: The uptake and intracellular trafficking of sphingolipids, which self-associate into plasma membrane microdomains, is associated with many pathological conditions, including viral and toxin infection, lipid storage disease, and neurodegenerative disease. However, the means available to label the trafficking pathways of sphingolipids in live cells are extremely limited. In order ... More
A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick disease.
Authors:He X, Chen F, Dagan A, Gatt S, Schuchman EH
Journal:Anal Biochem
PubMed ID:12633609
'Acid sphingomyelinase (ASM; sphingomyelin phosphodiesterase, EC 3.1.4.12) is the lysosomal enzyme that hydrolyzes sphingomyelin (SPM) to phosphorylcholine and ceramide. An inherited deficiency of ASM activity results in Types A and B Niemann-Pick disease (NPD). In this study we report a new assay method to detect ASM activity and diagnose NPD ... More
Synthesis of fluorescent substrates and their application to study of sphingolipid metabolism in vitro and in intact cells.
Authors:Dagan A, Agmon V, Gatt S, Dinur T
Journal:Methods Enzymol
PubMed ID:11070879
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