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Invitrogen
Complement C5b Monoclonal Antibody (aE11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
DIA 011-01-02
应用
建议稀释比
已发表文章
产品规格
种属反应
Horse,
Human,
Non-human primate,
Pig
已发表种属
Human,
Pig
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
aE11
抗原
Purified C5b-9.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.00 mg/mL
规格
400 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
4°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
DIA 011-01-02 binds both membrane-bound MAC and fluid-phase SC5b-9 complexes from human, porcine, baboon and equine samples.
DIA 011-01-02 has been successfully used in ELISA and IHC applications. This antibody is not recommended for Western blotting as the epitope is destroyed during the process.
靶标信息
C5b-9 is also known as the TCC. TCC consists of C5b, C6, C7, C8 and C9. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The complex contains neoantigens that are absent from the individual native components and the monoclonal antibody DIA 011-01 is directed against a neoepitope exposed in C9 when incorporated into TCC.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; CHE1; Complement C5; complement component C5; FLJ17816; FLJ17822; MGC142298
基因别名: C5; CPAMD4
Entrez Gene ID: (Horse) 100067655, (Pig) 414437
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
