Recognition of a virus-encoded ligand by a natural killer cell activation receptor.
Authors Smith Hamish R C; Heusel Jonathan W; Mehta Indira K; Kim Sungjin; Dorner Brigitte G; Naidenko Olga V; Iizuka Koho; Furukawa Hiroshi; Beckman Diana L; Pingel Jeanette T; Scalzo Anthony A; Fremont Daved H; Yokoyama Wayne M;
JournalProc Natl Acad Sci U S A
PubMed ID12060703
Natural killer (NK) cells express inhibitory and activation receptors that recognize MHC class I-like molecules on target cells. These receptors may be involved in the critical role of NK cells in controlling initial phases of certain viral infections. Indeed, the Ly49H NK cell activation receptor confers in vivo genetic resistance ... More