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引用和文献 (86)
Invitrogen™
MQAE（N-(乙氧羰基甲基)-6-甲氧基喹啉鎓溴化物）
MQAE 是 6-甲氧基喹啉鎓衍生物，是细胞内 Cl- 的荧光指示剂。该染料可通过扩散限制性碰撞淬灭检测离子。与 SPQ 相比，MQAE 具有更高的了解更多信息
| 货号 | 数量 |
|---|---|
| E3101 | 100 mg |
货号 E3101
价格（CNY)
3,140.00
飞享价
Ends: 31-Dec-2025
4,228.00共减 1,088.00 (26%)
Each
数量:
100 mg
价格（CNY)
3,140.00
飞享价
Ends: 31-Dec-2025
4,228.00共减 1,088.00 (26%)
Each
MQAE 是 6-甲氧基喹啉鎓衍生物，是细胞内 Cl- 的荧光指示剂。该染料可通过扩散限制性碰撞淬灭检测离子。与 SPQ 相比，MQAE 具有更高的 Cl- 敏感性和更高的荧光量子得率；因此，目前两种指示剂中它的使用更广泛。
了解更多有关离子指示剂（包括钙、钾、pH 值和膜电位指示剂）的信息›
了解更多有关离子指示剂（包括钙、钾、pH 值和膜电位指示剂）的信息›
仅供科研使用。不可用于诊断程序。
规格
检测方法荧光
染料类型基于荧光染料
数量100 mg
运输条件室温
适用于（应用）细胞活力与增殖
适用于（设备）共聚焦显微镜, 流式细胞仪
产品类型MQAE
Unit SizeEach
内容与储存
在冷冻冰箱（-5°C 至 -30°C）中避光储存。
引用和文献 (86)
引用和文献
Abstract
Noninvasive measurement of chloride concentration in rat olfactory receptor cells with use of a fluorescent dye.
Journal:Am J Physiol Cell Physiol
PubMed ID:11350733
Inwardly directed Ca(2+)-dependent chloride currents are thought to prolong and boost the odorant-induced transient receptor currents in olfactory cilia. Cl(-) inward current, of course, requires a sufficiently high intracellular Cl(-) concentration ([Cl(-)](i)). In previous measurements using a fluorescent Cl(-) probe, N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide (MQAE), [Cl(-)](i) of newt olfactory cells was estimated
TRPV1 acts as proton channel to induce acidification in nociceptive neurons.
Journal:J Biol Chem
PubMed ID:15173182
The low extracellular pH of inflamed or ischemic tissues enhances painful sensations by sensitizing and activating the vanilloid receptor 1 (TRPV1). We report here that activation of TRPV1 results in a marked intracellular acidification in nociceptive dorsal root ganglion neurons and in a heterologous expression system. A characterization of the
Mechanistic studies of lantibiotic-induced permeabilization of phospholipid vesicles.
Journal:Biochemistry
PubMed ID:7849020
'Nisin is a cationic polycyclic bacteriocin secreted by some lactic acid bacteria. Nisin has previously been shown to permeabilize liposomes. The interaction of nisin was analyzed with liposomes prepared of the zwitterionic phosphatidylcholine (PC) and the anionic phosphatidylglycerol (PG). Nisin induces the release of 6-carboxyfluorescein and other small anionic fluorescent
Determination of the intracellular free chloride concentration in rat brain synaptoneurosomes using a chloride-sensitive fluorescent indicator.
Journal:Biochim Biophys Acta
PubMed ID:8274496
'The chloride-sensitive fluorescent indicator MQAE (N-(6-methoxyquinolyl) acetoacetyl ester) has been used for determination of the intracellular free chloride concentration in rat brain synaptoneurosomes. Loading of the synaptoneurosomes with MQAE occurs by transmembrane diffusion. Calibration of the intracellular MQAE was done by determining the correlation between fluorescence intensity and intrasynaptoneurosomal Cl-
Effects of sasanquasaponin on ischemia and reperfusion injury in mouse hearts.
Journal:J Pharmacol Sci
PubMed ID:15037817
'We investigated effects of sasanquasaponin (SQS), a traditional Chinese herb''s effective component, on ischemia and reperfusion injury in mouse hearts and the possible role of intracellular Cl- homeostasis on SQS''s protective effects during ischemia and reperfusion. An in vivo experimental ischemia model was made in mice (weight 27-45 g) using