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引用和文献 (30)
Invitrogen™
表皮生长因子、生物素-XX 偶联物（生物素 EGF）
该纯化的表皮生长因子 (EGF) 在 N- 末端氨基酸上含有一个生物素-XX 分子。生物素-XX EGF 具有长间隔臂，可增强探针对 EGF了解更多信息
| 货号 | 数量 |
|---|---|
| E3477 | 20 μg |
货号 E3477
价格（CNY)
7,540.00
Each
数量:
20 μg
价格（CNY)
7,540.00
Each
该纯化的表皮生长因子 (EGF) 在 N- 末端氨基酸上含有一个生物素-XX 分子。生物素-XX EGF 具有长间隔臂，可增强探针对 EGF 受体的亲和力，并有利于结合标记，如染料–链霉亲和素分子、Qdot™ 纳米晶体–链霉亲和素分子或酶偶联链霉亲和素。标记的 EGF 使得科学家能够研究受体-膜相互作用、研究受体分布、计算与 EGF 与受体相互作用的速率常数等。
表皮生长因子规格：
• EGF 分子：53 个氨基酸，MW=6,045 Da
• 每个 EGF 分子上的生物素-XX 分子数量：1 个
查找荧光 EGF 偶联物
除了生物素化 EGF，我们提供了与选择的荧光链霉素亲和素标记预复合的生物素化 EGF 以及直接与某些荧光染料标记的 EGF。查看 Molecular Probes™ 手册中用于追踪受体结合和吞噬作用的探针—第 16.1 节，了解有关这些产品的更多信息。
仅供科研使用。不可用于人或动物的治疗或诊断。
表皮生长因子规格：
• EGF 分子：53 个氨基酸，MW=6,045 Da
• 每个 EGF 分子上的生物素-XX 分子数量：1 个
查找荧光 EGF 偶联物
除了生物素化 EGF，我们提供了与选择的荧光链霉素亲和素标记预复合的生物素化 EGF 以及直接与某些荧光染料标记的 EGF。查看 Molecular Probes™ 手册中用于追踪受体结合和吞噬作用的探针—第 16.1 节，了解有关这些产品的更多信息。
仅供科研使用。不可用于人或动物的治疗或诊断。
仅供科研使用。不可用于诊断程序。
规格
检测方法荧光
标签或染料生物素 & 其他半抗原
数量20 μg
运输条件湿冰
形式固体
产品类型表皮生长因子
Unit SizeEach
内容与储存
在冰箱（-5 至 -30°C）中储存。
引用和文献 (30)
引用和文献
Abstract
Localization of EGF receptors in frozen tissue sections by antibody and biotinylated EGF-based techniques.
Journal:J Histochem Cytochem
PubMed ID:8308248
'We developed a sensitive EGF receptor detection method for frozen tissue sections using biotinylated EGF as the primary reagent. The method was directly compared with an immunohistochemical technique based on an anti-EGF receptor monoclonal antibody (MAb EGFR1) in normal human and rat tissues and in human tumors. The method was
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway.
Journal:J Cell Biol
PubMed ID:12975344
'While evidence is accumulating that phosphoinositide signaling plays a crucial role in growth factor and hormone receptor down-regulation, this signaling pathway has also been proposed to regulate endosomal membrane transport and multivesicular endosome biogenesis. Here, we have followed the fate of the down-regulated EGF receptor (EGFR) and bulk transport (fluid
Retention of biologic activity of human epidermal growth factor following conjugation to a blood-brain barrier drug delivery vector via an extended poly(ethylene glycol) linker.
Journal:Bioconjug Chem
PubMed ID:9893961
'Human brain gliomas overexpress the receptor for epidermal growth factor (EGF), and radiolabeled EGF is a potential peptide radiopharmaceutical for imaging human brain tumors, should this peptide be made transportable through the blood-brain barrier (BBB) in vivo. Peptide drug delivery to the brain may be facilitated by conjugating peptide radiopharmaceuticals
In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic.
Journal:Am J Pathol
PubMed ID:8579105
'Recent immunocytochemical and morphometric studies in amyotrophic lateral sclerosis, Alzheimer's disease (AD), and aging indicate that the neuronal Golgi apparatus is a reliable index of activity or degeneration. To further evaluate a possible role of the Golgi apparatus in the pathogenesis of AD, we examined by double labeling the neuronal
Targeted cellular delivery of quantum dots loaded on and in biotinylated liposomes.
Journal:Bioconjug Chem
PubMed ID:20715851
'We describe the preparation, biophysical characterization, and receptor-mediated cellular internalization of biotinylated lipid particles (BLPs) loaded on the surface and internally with two distinct (colors) of quantum dot (QD) probes. BLPs were formulated with 1.4 and 2.7 mol % PEG-lipids containing either a fusogenic or pH-sensitive lipid to promote bilayer