Noninflammatory chronic pelvic pain syndrome: immunological study in blood, ejaculate and prostate tissue.
AuthorsJohn H, Barghorn A, Funke G, Sulser T, Hailemariam S, Hauri D, Joller-Jemelka H
JournalEur Urol
PubMed ID11173942
'The aim of this prospective study was to observe immunophenotypic patterns in patients with noninflammatory chronic pelvic pain syndrome (Cat IIIB CPPS) for further description and as possible surrogate markers for diagnosis and treatment.' ... More
Lower serum DHEAS levels are associated with a higher degree of physical disability and depressive symptoms in middle-aged to older African American women.
AuthorsHaren MT, Malmstrom TK, Banks WA, Patrick P, Miller DK, Morley JE
JournalMaturitas
PubMed ID17451893
Changes in androgen levels and associations with chronic disease, physical and neuropsychological function and disability in women over the middle to later years of life are not well understood and have not been extensively studied in African American women. ... More
Concentration of soluble CD4, CD8 and CD25 receptors in early localized and early disseminated Lyme borreliosis.
AuthorsZajkowska J, Hermanowska-Szpakowicz T, Swierzbinska R
JournalInfection
PubMed ID11339478
The aim of this study was to evaluate the concentrations of soluble CD4, CD8 and CD25 antigens in the serum of patients with early LocaLized, (group I, n = 22 patients) and early disseminated Lyme borreliosis (group II n = 23 patients), before and after antibiotic therapy compared with controls ... More
Predominance of Th1 cytokine in peripheral blood and pathological tissues of patients with active untreated adult onset Still's disease.
AuthorsChen DY, Lan JL, Lin FJ, Hsieh TY, Wen MC
JournalAnn Rheum Dis
PubMed ID15361391
To determine the type 1 T helper (Th1)/type 2 T helper (Th2) balance in the peripheral blood (PB) and pathological tissues of patients with active untreated adult onset Still's disease (AOSD). ... More
The predictive value of serum interleukins in recurrent respiratory papillomatosis: a preliminary study.
AuthorsSnowden RT, Thompson J, Horwitz E, Stocks RM
JournalLaryngoscope
PubMed ID11224768
IL-2 is the primary interleukin responsible for activation of the cell-mediated (Th1) arm of the immune response. Our objective was to determine whether a correlation existed between circulating levels of interleukin-2 as well as its soluble receptor (sIL-2R) and the clinical course of recurrent respiratory papillomatosis. ... More
Role of interleukin-18 and T-helper type 1 cytokines in the development of Mycoplasma pneumoniae pneumonia in adults.
AuthorsTanaka H, Narita M, Teramoto S, Saikai T, Oashi K, Igarashi T, Abe S
JournalChest
PubMed ID12006434
Interleukin (IL)-18 is a proinflammatory cytokine, originally termed interferon (IFN)-gamma-inducing factor, which promotes T-helper type 1 (Th1) cytokine responses. We recently reported that serum IL-18 levels were elevated in children with Mycoplasma pneumoniae pneumonia (MP). In this study, we investigated the contribution of IL-18 to the infection and assessed the ... More
Immunological and molecular analysis of B lymphocytes in low-grade MALT lymphoma of the stomach. Are there any useful markers for predicting outcome after Helicobacter pylori eradication?
AuthorsMatsushima Y, Kinoshita Y, Fukui H, Maekawa T, Yazumi S, Okada A, Nakase H, Kawanami C, Iwano M, Hashimoto K, Takeda Z, Okazaki K, Chiba T
JournalJ Gastroenterol
PubMed ID12108676
Although Helicobacter pylori eradication is effective in treating low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma, the condition in some patients deteriorates even after the eradication. Therefore, it is important to predict the disease outcome before starting H. pylori eradication. We investigated the usefulness of flow cytometry, quantifying CD19- and CD20-positive ... More
Slower rates of clearance of viral load and virus-containing immune complexes in patients with dengue hemorrhagic fever.
AuthorsWang WK, Chen HL, Yang CF, Hsieh SC, Juan CC, Chang SM, Yu CC, Lin LH, Huang JH, King CC
JournalClin Infect Dis
PubMed ID16983615
Although previous studies have revealed the contribution of an initial high level of dengue virus replication to the severe and potentially life-threatening diseases dengue hemorrhagic fever (DHF) and dengue shock syndrome, the involvement of dengue virus in the immunopathological processes during the transition from fever to defervescence, which is a ... More
The immunomodulatory effects of thalidomide on human immunodeficiency virus-infected children.
AuthorsHanekom WA, Hughes J, Haslett PA, Apolles P, Ganiso V, Allin R, Goddard E, Hussey GD, Kaplan G
JournalJ Infect Dis
PubMed ID11598844
The safety and immune effects of low-dose thalidomide treatment (3 mg/kg/day for 28 days) were evaluated in a study involving 8 South African human immunodeficiency virus (HIV)-infected children. The children were 7-69 months old and in disease stages A1-C3. Thalidomide therapy did not affect virus load, even though none of ... More
Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study.
AuthorsYoshihara Y, Tsukazaki T, Osaki M, Nakashima M, Hasui K, Shindo H
JournalArthritis Res Ther
PubMed ID15225370
Human T cell leukaemia virus type I (HTLV-I) is known to be involved in late-onset chronic polyarthritis as HTLV-I-associated arthropathy. However, it is unclear whether HTLV-I infection could modify the pathophysiology of osteoarthritis (OA). In this study we compared several inflammatory cytokines, such as C-terminal parathyroid hormone-related peptide (C-PTHrP), soluble ... More