Etanercept reduces the serum levels of interleukin-23 and macrophage inflammatory protein-3 alpha in patients with rheumatoid arthritis.
AuthorsKageyama Y, Ichikawa T, Nagafusa T, Torikai E, Shimazu M, Nagano A
JournalRheumatol Int
PubMed ID17619881
'The purpose of this study was to analyze the effect of the soluble TNF-alpha receptor etanercept on the serum levels of IL-16, IL-17, IL-23, and macrophage inflammatory protein-3alpha (MIP-3alpha) in rheumatoid arthritis (RA) patients. Twenty-two patients with RA were administered etanercept once or twice a week for more than 6 ... More
Transient elevation of interleukin-16 levels at the initial stage of meningitis in children.
AuthorsSuzuki T, Ishiguro A, Shimbo T
JournalClin Exp Immunol
PubMed ID12605702
IL-16 is an immunomodulatory cytokine that is characterized by chemotactic activity and stimulation of proinflammatory cytokine expression in monocytic cells. We studied IL-16 using ELISA in children with meningitis. When meningeal symptoms existed, IL-16 levels were high in the cerebrospinal fluid (CSF) of both bacterial (939 +/- 877 ng/l, n ... More