The impact of ranitidine on monocyte responses in the context of solid tumors.
AuthorsVila-Leahey A, Rogers D, Marshall JS
JournalOncotarget
PubMed ID26863636
Monocytes and myeloid derived suppressor cells (MDSC) have been implicated on the regulation of tumor growth. Histamine is also important for regulating MDSC responses. Oral administration of the H2 receptor antagonist ranitidine can inhibit breast tumor growth and metastasis. In the current study, we examined the impact of oral ranitidine ... More