Serum Markers in Rheumatoid Arthritis: A Longitudinal Study of Patients Undergoing Infliximab Treatment.
AuthorsSelaas O, Nordal HH, Halse AK, Brun JG, Jonsson R, Brokstad KA
Journal
PubMed ID26788062
Objective. The aim of this study was to investigate the clinical effect and serum markers in a cohort of rheumatoid arthritis patients with moderate to high disease activity, participating in an open clinical phase IV study conducted in Norway between 2001 and 2003 receiving infliximab treatment. Method. A total of ... More
On the prospect of serum exosomal miRNA profiling and protein biomarkers for the diagnosis of ascending aortic dilatation in patients with bicuspid and tricuspid aortic valve.
AuthorsGallo A, Agnese V, Coronnello C, Raffa GM, Bellavia D, Conaldi PG, Pilato M, Pasta S
JournalInt J Cardiol
PubMed ID30297190
To determine the impact of circulating miRNA and protein activity on the severity of ascending aortic dilatation in patients with bicuspid (BAV) and tricuspid aortic valve (TAV). ... More
Piperlongumine inhibits the proliferation, migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis.
AuthorsXu S, Xiao Y, Zeng S, Zou Y, Qiu Q, Huang M, Zhan Z, Liang L, Yang X, Xu H
JournalInflamm Res
PubMed ID29119225
Recent studies have indicated that piperlongumine (PLM) may exert anti-inflammatory effects. In the present study, we determined the effect of PLM on the proliferation, apoptosis, migration and invasion of fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA) (referred to herein as RA FLS). We further explored the mechanisms by ... More