Fluorescein-5-(and-6)-Sulfonic Acid, Trisodium Salt
Fluorescein-5-(and-6)-Sulfonic Acid, Trisodium Salt
Citations & References (38)
Invitrogen™

Fluorescein-5-(and-6)-Sulfonic Acid, Trisodium Salt

The cell-impermeant fluorescein-5-(and-6)-sulfonic acid can be used as a non-fixable polar tracer to investigate fusion, lysis and gap-junctional communication.Read more
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Catalog NumberQuantity
F1130100 mg
Catalog number F1130
Price (CNY)
2,360.00
Online Exclusive
Ends: 31-Dec-2025
3,198.00
Save 838.00 (26%)
Each
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Quantity:
100 mg
Price (CNY)
2,360.00
Online Exclusive
Ends: 31-Dec-2025
3,198.00
Save 838.00 (26%)
Each
Add to cart
The cell-impermeant fluorescein-5-(and-6)-sulfonic acid can be used as a non-fixable polar tracer to investigate fusion, lysis and gap-junctional communication.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Detection MethodFluorescence
For Use With (Equipment)Fluorescence Microscope
Molecular FormulaC20H9Na3O8S
Quantity100 mg
Recommended StorageStore at room temperature and protect from light.
Shipping ConditionRoom Temperature
Sub Cellular LocalizationCell Membranes & Lipids
ColorGreen
Physical FormSolid
Product TypeCell Tracer
Unit SizeEach

Citations & References (38)

Citations & References
Abstract
Rapid development of vasopressin-induced hydroosmosis in kidney collecting tubules measured by a new fluorescence technique.
Authors:Kuwahara M, Berry CA, Verkman AS
Journal:Biophys J
PubMed ID:3224145
'The pre-steady-state kinetics of the vasopressin-induced increase in collecting tubule osmotic water permeability (Pf) has been measured by a new fluorescence technique. Isolated cortical collecting tubules (CCT) from rabbit kidney were perfused with physiological buffers containing the impermeant fluorophores fluorescein sulfonate (FS) and pyrenetetrasulfonic acid (PTSA). Tubules were subject to ... More
The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of intestinal epithelia.
Authors:Banan A, Farhadi A, Fields JZ, Zhang LJ, Shaikh M, Keshavarzian A
Journal:J Pharmacol Exp Ther
PubMed ID:12606598
'Using intestinal (Caco-2) cells, we found that oxidant-induced disruption of barrier integrity requires microtubule disassembly. Protein kinase C (PKC)-delta isoform seems to be essential for disruption, but the mechanism is unknown. Because inducible nitric-oxide synthase (iNOS) is key to oxidant stress, we hypothesized that PKC-delta activation is essential in oxidant-induced ... More
Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants.
Authors:Banan A, Fields JZ, Zhang Y, Keshavarzian A
Journal:Am J Physiol Gastrointest Liver Physiol
PubMed ID:11447022
'Loss of intestinal barrier integrity is associated with oxidative inflammatory GI disorders including inflammatory bowel disease. Using monolayers of human intestinal epithelial (Caco-2) cells, we recently reported that epidermal growth factor (EGF) protects barrier integrity against oxidants by stabilizing the microtubule cytoskeleton, but the mechanism downstream of the EGF receptor ... More
Activation of delta-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia.
Authors:Banan A, Fields JZ, Farhadi A, Talmage DA, Zhang L, Keshavarzian A
Journal:J Pharmacol Exp Ther
PubMed ID:12235228
'Using monolayers of intestinal (Caco-2) cells, we showed that oxidants disassemble the microtubule cytoskeleton and disrupt barrier integrity (permeability) (Banan et al., 2000a). Because exposure of our parental cells to oxidants causes protein kinase C (PKC)-delta to be translocated to particulate fractions, we hypothesized that PKC-delta activation is required for ... More
Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport.
Authors:Folkesson HG, Matthay MA, Frigeri A, Verkman AS
Journal:J Clin Invest
PubMed ID:8609221
'Water movement across the airway epithelium is important for regulation of the volume and composition of airspace fluid. A novel approach is reported here to measure osmotic and diffusional water permeability in intact airways. Small airways (100-200 microns diameter, 1-2 mm length) from guinea pig lung were microdissected and perfused ... More
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