Synaptic connections between layer 5B pyramidal neurons in mouse somatosensory cortex are independent of apical dendrite bundling.
AuthorsKrieger P, Kuner T, Sakmann B,
JournalJ Neurosci
PubMed ID17959790
'Rodent somatosensory barrel cortex is organized both physiologically and anatomically in columns with a cross-sectional diameter of 100-400 microm. The underlying anatomical correlate of physiologically defined, much narrower minicolumns (20-60 microm in diameter) remains unclear. The minicolumn has been proposed to be a fundamental functional unit in the cortex, and ... More
Signalling pathway of nitric oxide in synaptic GABA release in the rat paraventricular nucleus.
AuthorsLi DP, Chen SR, Finnegan TF, Pan HL
JournalJ Physiol
PubMed ID14678495
In the paraventricular nucleus (PVN) of the hypothalamus, nitric oxide (NO) inhibits sympathetic outflow through increased GABA release. However, the signal transduction pathways involved in its action remain unclear. In the present study, we determined the role of cGMP, soluble guanylyl cyclase, and protein kinase G in the potentiating effect ... More