Fluorescent microangiography (FMA): an improved tool to visualize the pulmonary microvasculature.
AuthorsDutly AE, Kugathasan L, Trogadis JE, Keshavjee SH, Stewart DJ, Courtman DW
JournalLab Invest
PubMed ID16518405
Visualization of the complex lung microvasculature and resolution of its three-dimensional architecture remains a difficult experimental challenge. We present a novel fluorescent microscopy technique to visualize both the normal and diseased pulmonary microvasculature. Physiologically relevant pulmonary perfusion conditions were applied using a low-viscosity perfusate infused under continuous airway ventilation. Intensely ... More
Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay.
AuthorsLebani K, Jones ML, Watterson D, Ranzoni A, Traves RJ, Young PR, Mahler SM
JournalPLoS One
PubMed ID28683141
The multidimensional nature of dengue virus (DENV) infections, which can be caused by four distinct serotypes of the virus, complicates the sensitivity of assays designed for the diagnosis of infection. Different viral markers can be optimally detected at different stages of infection. Of particular clinical importance is the early identification ... More