Counting dendritic spines in brain tissue slices by image correlation spectroscopy analysis.
AuthorsWiseman PW, Capani F, Squier JA, Martone ME
JournalJ Microsc
PubMed ID11879432
Growth of new micrometre sized projections called dendritic spines in neurones has been linked to the encoding of long-term memories in vertebrates. Numerous studies have been carried out at both the light and electron microscopy level to quantify dendritic spine densities in brain tissue in laboratory animals. Currently, such efforts ... More
Angiogenesis monitored by perfusion with a space-filling microbead suspension.
AuthorsSpringer ML, Ip TK, Blau HM
JournalMol Ther
PubMed ID10933915
Numerous laboratories are focusing efforts on delivering gene products to induce or prevent the development of new blood vessels in adults, with the hope of rescuing ischemic tissues, circumventing cardiac bypass surgery, or inhibiting tumor growth. Current approaches to the assessment of vascular continuity involve the introduction of either dyes ... More