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Abnova
ID1 Monoclonal Antibody (5D9)
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产品信息
H00003397-M05A
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgM, kappa
分类
Monoclonal
类型
Antibody
克隆号
5D9
抗原
ID1 (AAH00613.1, 1 a.a. approximately 155 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
保存液
ascites
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MKVASGSTAT AAAGPSCALK AGKTASGAGE VVRCLSEQSV AISRCAGGAG ARLPALLDEQ QVNVLLYDMN GCYSRLKELV PTLPQNRKVS KVEILQHVID YIRDLQLELN SESEVGTPGG RGLPVRAPLS TLNGEISALT AEAACVPADD RILCR
靶标信息
ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. It has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHb24; Class B basic helix-loop-helix protein 24; dJ857M17.1.2; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein); DNA-binding protein inhibitor ID-1; Id1; Inhibitor of differentiation 1; Inhibitor of DNA binding 1; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; inhibitor of DNA binding 1, HLH protein; transcription regulator helix-loop-helix protein; unnamed protein product
基因别名: BHLHB24; ID; ID1
UniProt ID: (Human) P41134
Entrez Gene ID: (Human) 3397
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
endothelial cell morphogenesis
apoptotic process
transforming growth factor beta receptor signaling pathway
heart development
circadian rhythm
negative regulation of transcription by transcription factor localization
positive regulation of gene expression
negative regulation of gene expression
neuron differentiation
BMP signaling pathway
protein destabilization
collagen metabolic process
regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
blood vessel endothelial cell migration
negative regulation of osteoblast differentiation
regulation of angiogenesis
negative regulation of transcription, DNA-templated
response to antibiotic
rhythmic process
blood vessel morphogenesis
lung morphogenesis
lung vasculature development
endothelial cell apoptotic process
negative regulation of cold-induced thermogenesis
negative regulation of endothelial cell apoptotic process
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