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Abnova
TOPORS Monoclonal Antibody (5G9)
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产品信息
H00010210-M14A
产品规格
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
5G9
抗原
TOPORS (NP_005793, 98 a.a. approximately 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: SPDSKCPICL DRFDNVSYLD RCLHKFCFRC VQEWSKNKAE CPLCKQPFDS IFHSVRAEDD FKEYVLRPSY NGSFVTPDRR FRYRTTLTRE RNASVYSPSG PVNRRTTT
靶标信息
Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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