Characterization of a human plasma membrane heme transporter in intestinal and hepatocyte cell lines.
AuthorsWorthington MT, Cohn SM, Miller SK, Luo RQ, Berg CL
JournalAm J Physiol Gastrointest Liver Physiol
PubMed ID11352810
Heme is the most bioavailable form of dietary iron and a component of many cellular proteins. Controversy exists as to whether heme uptake occurs via specific transport mechanisms or passive diffusion. The aims of this study were to quantify cellular heme uptake with a fluorescent heme analog and to determine ... More