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Thermo Scientific Chemicals
Piroxicam
CAS: 36322-90-4 | C15H13N3O4S | 331.346 g/mol
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化学标识符
CAS36322-90-4
IUPAC Name(3E)-3-{hydroxy[(pyridin-2-yl)amino]methylidene}-2-methyl-3,4-dihydro-2H-1λ⁶,2-benzothiazine-1,1,4-trione
Molecular FormulaC15H13N3O4S
InChI KeyLDJVNWFKNMYYNT-FYWRMAATSA-N
SMILESCN1C(=C(O)NC2=CC=CC=N2)C(=O)C2=CC=CC=C2S1(=O)=O
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规格
规格表
规格表Melting Point196-204°C
Appearance (Color)White to pale yellow to pale green
Assay (unspecified)≥97.0%
FormSolid
Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor. Studies show that Piroxicam blocks release of platelet ADP, and inhibits Cox-1 more potently than Cox-2.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor. Studies show that Piroxicam blocks release of platelet ADP, and inhibits Cox-1 more potently than Cox-2.
Solubility
Soluble in water, ethanol, chloroform, ethyl acetate.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor. Studies show that Piroxicam blocks release of platelet ADP, and inhibits Cox-1 more potently than Cox-2.
Solubility
Soluble in water, ethanol, chloroform, ethyl acetate.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- V. Tantishaiyakul.; N. Kaewnopparat.; S. Ingkatawornwong. Properties of solid dispersions of piroxicam in polyvinylpyrrolidone K-30. International Journal of Pharmaceutics. 1996, 143,(1), 59-66.
- V. Tantishaiyakul.; N. Kaewnopparat.; S. Ingkatawornwong. Properties of solid dispersions of piroxicam in polyvinylpyrrolidone K-30. International Journal of Pharmaceutics. 1999, 181,(2), 143-151.