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Thermo Scientific Chemicals
Domperidone
Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier | CAS: 57808-66-9 | C22H24ClN5O2 | 425.917 g/mol
| 货号 | 数量 |
|---|---|
| J63681.MC 又称 J63681-MC | 100 mg |
规格
CAS57808-66-9
ChEBICHEBI:31515
化学名称或材料Domperidone
颜色White
EINECS 编号260-968-7
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Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.
Solubility
Slightly soluble in water.
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.
Solubility
Slightly soluble in water.
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
RUO – Research Use Only
General References:
- Pierre M. Laduron.; Josee E. Leysen. Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity. Biochemical Pharmacology. 1979, 28, (14), 2161-2165.
- Jai D. Kohli.; Dana Glock.; Leon I. Goldberg. Selective DA2 versus DA1 antagonist activity of domperidone in the periphery. European Journal of Pharmacology. 1983, 89, (1-2), 137-141.