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Sulfamethoxazole, CAS # 723-46-6, is a sulfonamide antibiotic that inhibits folic acid synthesis in bacteria and prevents cell division and growth. | CAS: 723-46-6 | C10H11N3O3S | 253.276 g/mol

货号	数量	包装
J66565.22 又称 J66565-22	100 g	Plastic bottle

货号 J66565.22

又称 J66565-22

价格（CNY)

100 g

Plastic bottle

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化学标识符

CAS723-46-6

IUPAC Name4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide

Molecular FormulaC10H11N3O3S

InChI KeyJLKIGFTWXXRPMT-UHFFFAOYSA-N

SMILESCC1=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NO1

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FormPowder or crystals or crystalline powder

Loss on Drying≤0.5%

Appearance (Color)White to off-white

Assay (unspecified)≥97.5%

Residue on ignition≤0.5%

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A broad spectrum bacteriostatic sulfonamide antibiotic

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Sulfamethoxazole is an antibiotic composed of an isoxazole with a 4-aminobenzenesulfonamido and methyl-group substitution at positions 5 and 3, respectively
Sulfamethoxazole carries out most of its action through the inhibition of dihydropteroate synthase, the enzyme responsible for the synthesis of the precursor of folic acid; inhibition of folic acid synthesis prevents DNA replication and cell division in susceptible bacteria

Application

Sulfamethoxazole can elicit an allergic response and may be useful for immune cell studies in laboratory settings
Sulfamethoxazole is suitable for laboratory research on infection, environmental pollution, and the physiology of susceptible bacteria

RUO – Research Use Only

General References:

Xiong JQ, Govindwar S, Kurade MB, Paeng KJ, Roh HS, Khan MA, Jeon BH. Toxicity of sulfamethazine and sulfamethoxazole and their removal by a green microalga, Scenedesmus obliquus. Chemosphere. 2019 Mar;218:551-558. doi: 10.1016/j.chemosphere.2018.11.146. Epub 2018 Nov 24. PMID: 30500716.
Ma R, Wang Y, Zou X, Hu K, Sun B, Fang W, Fu G, Yang X. Pharmacokinetics of sulfamethoxazole and trimethoprim in Pacific white shrimp, Litopenaeus vannamei, after oral administration of single-dose and multiple-dose. Environ Toxicol Pharmacol. 2017 Jun;52:90-98. doi: 10.1016/j.etap.2017.03.019. Epub 2017 Mar 28. PMID: 28410468.