'The Drosophila circadian oscillator consists of interlocked period (per)/timeless (tim) and Clock (Clk) transcriptional/translational feedback loops. Within these feedback loops, CLK and CYCLE (CYC) activate per and tim transcription at the same time as they repress Clk transcription, thus controlling the opposite cycling phases of these transcripts. CLK-CYC directly bind ... More
Monitoring foreign protein expression under baculovirus p10 and polh promoters in insect larvae.
Authors Cha H J; Dalal N G; Pham M Q; Kramer S F; Vakharia V N; Bentley W E;
JournalBiotechniques
PubMed ID12019794
Monitoring foreign protein expression under baculovirus p10 and polh promoters in insect larvae.
Heparin-binding protein (CAP37) is internalized in monocytes and increases LPS-induced monocyte activation.
AuthorsHeinzelmann M, Mercer-Jones MA, Flodgaard H, Miller FN
JournalJ Immunol
PubMed ID9605157
Previous studies have shown that the neutrophil-derived heparin-binding protein (HBP), also known as CAP37 or azurocidin, potentiates the LPS- induced release of proinflammatory cytokines (TNF-alpha, IL-1, and IL- 6) from isolated human monocytes. To date, the mechanisms by which HBP enhances LPS-induced monocyte activation have not been elucidated, and it ... More