loning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family.
AuthorsLi H, Chen J, Huang A, Stinson J, Heldens S, Foster J, Dowd P, Gurney AL, Wood W
JournalProc Natl Acad Sci U S A
PubMed ID10639155
'IL-17 is a T cell-derived cytokine that may play an important role in the initiation or maintenance of the proinflammatory response. Whereas expression of IL-17 is restricted to activated T cells, the IL-17 receptor is found to be widely expressed, a finding consistent with the pleiotropic activities of IL-17. We ... More