X-ray structure of the EmrE multidrug transporter in complex with a substrate.
AuthorsPornillos O, Chen YJ, Chen AP, Chang G,
JournalScience
PubMed ID16373573
EmrE is a prototype of the Small Multidrug Resistance family of efflux transporters and actively expels positively charged hydrophobic drugs across the inner membrane of Escherichia coli. Here, we report the x-ray crystal structure, at 3.7 angstrom resolution, of one conformational state of the EmrE transporter in complex with a ... More