Elevated serum insulin-like growth factor (IGF-1) and IGF binding protein-3 levels in patients with systemic sclerosis: possible role in development of fibrosis.
AuthorsHamaguchi Y, Fujimoto M, Matsushita T, Hasegawa M, Takehara K, Sato S,
JournalJ Rheumatol
PubMed ID19004037
OBJECTIVE: To examine serum concentrations of insulin-like growth factor (IGF-1) and IGF binding protein (IGFBP-3), a major carrier protein for IGF-1, in patients with systemic sclerosis (SSc); and to relate the results to clinical features in SSc. METHODS: Serum IGF-1 and IGFBP-3 levels in 92 Japanese patients with SSc were ... More