Methodologic issues in the measurement of interleukin-16 in clinical blood samples using immunoassays.
AuthorsGoihl A, Rolle AM, Kähne T, Reinhold A, Wrenger S, Reinhold D,
JournalCytokine
PubMed ID22239948
Quantitation of interleukin-16 (IL-16) in clinical blood samples has strongly increased, since IL-16 appears to be involved in the pathogenesis of several inflammatory diseases. IL-16 is synthesized in the cell cytoplasm as precursor protein (pro-IL-16), which can be processed by caspase-3 into N-terminal (N-IL-16) and C-terminal (C-IL-16) fragments. C-IL-16 is ... More