Immunobiologic implication of RANTES in seminal plasma of fertile, infertile and immunoinfertile men.
AuthorsNaz RK, Leslie MH,
JournalAm J Reprod Immunol
PubMed ID11076090
'To investigate the presence of Regulated on Activation, Normal T Expressed and Secreted (RANTES) in the seminal plasma of fertile, infertile, and immunoinfertile men in order to determine whether it has any role in fertility/infertility and in the modulation of immunogenicity of the sperm cell. The enzyme-linked immunosorbent assay was ... More
Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis.
AuthorsXu WT, Bian ZY, Fan QM, Li G, Tang TT,
JournalCancer Lett
PubMed ID19342158
In an effort to study the interaction between MSCs and osteosarcoma, we established an animal model of primary osteosarcoma in nude mice using Saos-2 cells. hMSCs, labeled with adv-GFP, were injected through the caudal vein. We observed that exogenous hMSCs targeted the osteosarcoma site and promoted its growth and pulmonary ... More
Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily.
AuthorsHensley LE, Young HA, Jahrling PB, Geisbert TW,
JournalImmunol Lett
PubMed ID11803049
Ebola virus (EBOV) infections are characterized by dysregulation of normal host immune responses. Insight into the mechanism came from recent studies in nonhuman primates, which showed that EBOV infects cells of the mononuclear phagocyte system (MPS), resulting in apoptosis of bystander lymphocytes. In this study, we evaluated serum levels of ... More