Contribution of interleukin 17A to the development and regulation of allergic inflammation in a murine allergic rhinitis model.
AuthorsQuan SH, Zhang YL, Han DH, Iwakura Y, Rhee CS,
JournalAnn Allergy Asthma Immunol
PubMed ID22541406
Interleukin (IL) 17A, a key cytokine of T(H)17 cells, is a well-known proinflammatory cytokine. Despite the important role of T(H)17 cells in acute airway inflammation, the role of IL-17A in allergic rhinitis (AR) remains unclear. To investigate the role of IL-17A in the allergic response in AR. Wild-type BALB/c and ... More