Study of the viral infections and cytokines associated with recurrent aphthous ulceration.
AuthorsLin SS, Chou MY, Ho CC, Kao CT, Tsai CH, Wang L, Yang CC,
JournalMicrobes Infect
PubMed ID15840465
'Mouth ulcers are one of the most common oral complaints. However, the association between oral ulceration and viruses and cytokines is uncertain. We detected the presence of human papilloma virus (HPV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV)-1, HSV-2 and human herpesvirus (HHV)-8 DNA in oral tissues by ... More
Apoptosis induction in Jurkat cells and sCD95 levels in women's sera are related with the risk of developing cervical cancer.
AuthorsAguilar-Lemarroy A, Romero-Ramos JE, Olimon-Andalon V, Hernandez-Flores G, Lerma-Diaz JM, Ortiz-Lazareno PC, Morgan-Villela G, Del Toro-Arreola S, Bravo-Cuellar A, Jave-Suarez LF,
JournalBMC Cancer
PubMed ID18405371
'Currently, there is clear evidence that apoptosis plays an important role in the development and progression of tumors. One of the best characterized apoptosis triggering systems is the CD95/Fas/APO-1 pathway; previous reports have demonstrated high levels of soluble CD95 (sCD95) in serum of patients with some types of cancer. Cervical ... More
Fas (APO-1/CD95) in inflammatory CNS diseases: intrathecal release in bacterial meningitis.
AuthorsFassbender K, Eschenfelder C, Hennerici M,
JournalJ Neuroimmunol
PubMed ID10378875
Release of Fas (APO-1, CD95), a type L-membrane protein which plays a crucial role in cytokine-mediated apoptosis was investigated in bacterial meningitis, viral meningoencephalitis and multiple sclerosis in vivo. After correction for bloodbrain-CSF-disruption, significantly increased intrathecal release of Fas was demonstrated exclusively in bacterial meningitis arguing for an apoptotic cell ... More