An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism.
AuthorsRosenblatt J, Raff MC, Cramer LP
JournalCurr Biol
PubMed ID11728307
'BACKGROUND: Simple epithelia encase developing embryos and organs. Although these epithelia consist of only one or two layers of cells, they must provide tight barriers for the tissues that they envelop. Apoptosis occurring within these simple epithelia could compromise this barrier. How, then, does an epithelium remove apoptotic cells without ... More
Lectin mapping reveals stage-specific display of surface carbohydrates in in vitro and haemolymph-derived cells of the entomopathogenic fungus Beauveria bassiana.
AuthorsWanchoo A, Lewis MW, Keyhani NO,
JournalMicrobiology
PubMed ID19608611
'The entomopathogenic fungus Beauveria bassiana and its insect host target represent a model system with which to examine host-pathogen interactions. Carbohydrate epitopes on the surfaces of fungal cells play diverse roles in processes that include adhesion, non-self recognition and immune invasion with respect to invertebrate hosts. B. bassiana produces a ... More
Biochemical and structural analysis of Helix pomatia agglutinin. A hexameric lectin with a novel fold.
AuthorsSanchez JF, Lescar J, Chazalet V, Audfray A, Gagnon J, Alvarez R, Breton C, Imberty A, Mitchell EP
JournalJ Biol Chem
PubMed ID16704980
'Helix pomatia agglutinin (HPA) is a N-acetylgalactosamine (GalNAc) binding lectin found in the albumen gland of the roman snail. As a constituent of perivitelline fluid, HPA protects fertilized eggs from bacteria and is part of the innate immunity system of the snail. The peptide sequence deduced from gene cloning demonstrates ... More
Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells.
Authors
JournalJ Immunol
PubMed ID28330897
SPEF2 functions in microtubule-mediated transport in elongating spermatids to ensure proper male germ cell differentiation.
Authors
JournalDevelopment
PubMed ID28619825
P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration.
Authors
JournalJ Cell Sci
PubMed ID31604795
IBD-Associated Atg16L1T300A Polymorphism Regulates Commensal Microbiota of the Intestine.
Authors
JournalFront Immunol
PubMed ID35154071
Galnt1 is required for normal heart valve development and cardiac function.
Authors
JournalPLoS One
PubMed ID25615642
Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression.
Authors
JournalJ Cell Sci
PubMed ID29093022
Cosmc-dependent mucin-type O-linked glycosylation is essential for podocyte function.