Involvement of endocytic organelles in the subcellular trafficking and localization of riboflavin.
AuthorsHuang SN, Phelps MA, Swaan PW
JournalJ Pharmacol Exp Ther
PubMed ID12721324
Previous studies by our laboratory have suggested the potential role of receptor-mediated endocytosis components in the cellular translocation of riboflavin (vitamin B2). To delineate the intracellular compartments and events involved in the internalization of riboflavin, we synthesized a rhodamine-labeled riboflavin conjugate to monitor its movement via fluorescent microscopy. Cellular uptake ... More