Multiplexed, particle-based detection of DNA using flow cytometry with 3DNA dendrimers for signal amplification.
AuthorsLowe M, Spiro A, Zhang YZ, Getts R
JournalCytometry A
PubMed ID15290714
'BACKGROUND: Complex mixtures of DNA may be found in environmental and medical samples. There is a need for techniques that can measure low concentrations of target DNAs. For a multiplexed, flow cytometric assay, we show that the signal-to-noise ratio for fluorescence detection may be increased with the use of 3DNA ... More