Titanium-Enriched Hydroxyapatite-Gelatin Scaffolds with Osteogenically Differentiated Progenitor Cell Aggregates for Calvaria Bone Regeneration.
AuthorsFerreira JR, Padilla R, Urkasemsin G, Yoon K, Goeckner K, Hu WS, Ko CC,
JournalTissue Eng Part A
PubMed ID23495972
'Adequate bony support is the key to re-establish both function and esthetics in the craniofacial region. Autologous bone grafting has been the gold standard for regeneration of problematic large bone defects. However, poor graft availability and donor-site complications have led to alternative bone tissue-engineering approaches combining osteoinductive biomaterials and three-dimensional ... More
Local phagocytic responses after murine infection with different forms of Fonsecaea pedrosoi and sclerotic bodies originating from an inoculum of conidiogenous cells.
AuthorsMachado AP, Silva MR, Fischman O,
JournalMycoses
PubMed ID19925569
'Fonsecaea pedrosoi is an important causative agent of chromoblastomycosis (CBM) especially in humid areas of the world; however, little is known about the infective forms of this agent that cause CBM. The aim of this study was to investigate the murine tissue response to inoculation with different forms of F. ... More
Prolonged infection by Fonsecaea pedrosoi after antigenic co-stimulation at different sites in experimental murine chromoblastomycosis.
AuthorsMachado AP, Silva MR, Fischman O,
JournalVirulence
PubMed ID21178410
'In the present study, we examined prolonged infection after antigenic co-stimulation by inoculation of the fungus Fonsecaea pedrosoi at two different sites in three mouse strains (BALB/c, Swiss, and C57BL/6). Using this murine model of infection, we showed that antigen induction of infection at more than one site led to ... More
Radio frequency radiation causes no nonthermal damage in enzymes and living cells.
AuthorsFortune JA, Wu BI, Klibanov AM,
JournalBiotechnol Prog
PubMed ID20572294
The ability of radio frequency radiation (RFR) to exert irreversible nonthermal (i.e., not caused by accompanying heat) effects on biologics has been widely debated due to a relative paucity of comprehensive critical details in published reports dealing with this issue. In this study, we used rigorous control over experimental conditions ... More