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引用和文献 (42)
Invitrogen™
LDS 751
LDS 751 是一种细胞渗透性的核酸染色剂，与 dsDNA 结合后的激发峰位于 ∼543 nm 波长处，由于具有较长的最大发射波长 (∼712 nm)了解更多信息
| 货号 | 数量 |
|---|---|
| L7595 | 10 mg |
货号 L7595
价格（CNY)
2,593.32
飞享价
Ends: 31-Dec-2026
3,446.00共减 852.68 (25%)
Each
数量:
10 mg
价格（CNY)
2,593.32
飞享价
Ends: 31-Dec-2026
3,446.00共减 852.68 (25%)
Each
LDS 751 是一种细胞渗透性的核酸染色剂，与 dsDNA 结合后的激发峰位于 ∼543 nm 波长处，由于具有较长的最大发射波长 (∼712 nm) 而特别适用于多色分析。LDS 751 与 dsDNA 结合后会导致荧光增强 ∼20 倍。
仅供科研使用。不可用于诊断程序。
规格
检测方法荧光
染料类型LDS 751
激发波长范围543⁄712
适用于（设备）流式细胞仪
形式实心
数量10 mg
运输条件室温
产品类型核酸染色剂
亚细胞定位细胞核，核酸, Nucleus
Unit SizeEach
内容与储存
包含1瓶 LDS 751 (10 mg)。 室温避光储存。
引用和文献 (42)
引用和文献
Abstract
Dyes providing increased sensitivity in flow-cytometric dye-efflux assays for multidrug resistance.
Journal:Cytometry
PubMed ID:7587707
In an effort to improve detection of P-glycoprotein-mediated multidrug resistance (mdr), several dyes were compared to rhodamine 123 (R123) in efflux assays. Two dyes (SY-38 and SY-3150) were found that provided better sensitivity. These dyes were effluxed by a cell line known to be mdr-positive (P388/R84) but not by an
Modulation of platelet-neutrophil interaction with pharmacological inhibition of fibrinogen binding to platelet GPIIb/IIIa receptor.
Journal:Thromb Haemost
PubMed ID:10064007
'The study investigated how drug inhibition of the GPIIb/IIIa receptor influences the interactions between platelets and leukocytes. These interactions are believed to play an important role in the etiology of the acute coronary syndromes. Thirty patients with unstable angina or non-Q-wave myocardial infarction were studied before the administration of tirofiban
Discriminating between damaged and intact cells in fixed flow cytometric samples.
Journal:Cytometry
PubMed ID:2460298
'A vital, nucleic acid stain (LDS-751) was used to discriminate intact from damaged cells in a flow cytometer even after the samples had been fixed with paraformaldehyde. Three major cell populations with different fluorescence properties with LDS-751 were found in the fixed samples. Cells not staining or only dimly staining
The Q-Prep system: effects on the apparent expression of leucocyte cell surface antigens.
Journal:Cytometry
PubMed ID:9149913
'To facilitate the analysis of immunolabelled peripheral blood or bone marrow leucocytes by flow cytometry, a number of reagents are available commercially that lyse erythrocytes and fix leucocytes. This study has investigated the effect on antibody-labelled whole blood of the Q-Prep procedure, in which erythrocytes are lysed with formic acid,
Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs.
Journal:Biochemistry
PubMed ID:16229491
'The P-glycoprotein efflux pump, an ABC superfamily member, can export a wide variety of hydrophobic drugs, natural products, and peptides from cells, powered by the energy of ATP hydrolysis. Transport substrates appear to first partition into the membrane and then interact with the protein within the cytoplasmic leaflet. Two drug