Cerebrospinal fluid levels of soluble amyloid precursor protein and ß-amyloid 42 in patients with multiple sclerosis, neuromyelitis optica and clinically isolated syndrome.
AuthorsMai W, Hu X, Lu Z, Peng F, Wang Y,
JournalJ Int Med Res
PubMed ID22289560
'Amyloid precursor protein (APP) accumulation in axonal ovoids is a sensitive marker for acute axonal injury in multiple sclerosis (MS) lesions. This study measured levels of a-cleaved soluble APP (a sAPP) and ß-amyloid 42 (Aß42) in the cerebrospinal fluid (CSF) of 42 MS, 10 neuromyelitis optica and 25 clinically isolated ... More