Lung development and susceptibility to ventilator-induced lung injury.
AuthorsKornecki A, Tsuchida S, Ondiveeran HK, Engelberts D, Frndova H, Tanswell AK, Post M, McKerlie C, Belik J, Fox-Robichaud A, Kavanagh BP,
JournalAm J Respir Crit Care Med
PubMed ID15640366
'Ventilator-induced lung injury has been predominantly studied in adults. To explore the effects of age and lung development on susceptibility to such injury. Ex vivo isolated nonperfused rat lungs (infant, juvenile, and adult) were mechanically ventilated where VT was based on milliliters per kilogram of body weight or as a ... More