MANT-GTP（2'-（或-3'）-O-（N-甲基氨茴酰）鸟苷 5'-三磷酸三钠盐）
MANT-GTP（2'-（或-3'）-<i>O</i>-（<i>N</i>-甲基氨茴酰）鸟苷 5'-三磷酸三钠盐）
引用和文献 (48)
Invitrogen™

MANT-GTP（2'-（或-3'）-O-（N-甲基氨茴酰）鸟苷 5'-三磷酸三钠盐）

核苷类似物 MANT GTP 的核糖基团经过修饰。MANT 荧光基团及其附着位置的紧凑性使得核苷类似物几乎不会干扰核苷酸-蛋白质相互作用。由于 MANT 荧光对荧光基团的环境敏感，因此可以直接检测核苷酸-蛋白质相互作用。MANT了解更多信息
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货号数量
M12415400 µL
货号 M12415
价格（CNY)
6,060.00
Each
添加至购物车
数量:
400 µL
价格（CNY)
6,060.00
Each
添加至购物车
核苷类似物 MANT GTP 的核糖基团经过修饰。MANT 荧光基团及其附着位置的紧凑性使得核苷类似物几乎不会干扰核苷酸-蛋白质相互作用。由于 MANT 荧光对荧光基团的环境敏感，因此可以直接检测核苷酸-蛋白质相互作用。MANT 核苷酸是用于检测核苷酸结合蛋白的结构及酶活性的重要探针。
仅供科研使用。不可用于诊断程序。
规格
标签或染料MANT（N-甲基氨茴酰）
产品类型MANT-GTP
数量400 µL
运输条件湿冰
最大浓度5 mM
Unit SizeEach
内容与储存
在冷冻冰箱（-5°C 至 -30°C）中避光储存。

引用和文献 (48)

引用和文献
Abstract
Authors:
Journal:
PubMed ID:11063593
Activation of the superoxide-generating NADPH oxidase by chimeric proteins consisting of segments of the cytosolic component p67(phox) and the small GTPase Rac1.
Authors:Alloul N, Gorzalczany Y, Itan M, Sigal N, Pick E
Journal:Biochemistry
PubMed ID:11724569
'Activation of the superoxide (O2(-))-generating NADPH oxidase of phagocytes is the consequence of the assembly of a membrane-associated flavocytochrome b(559) with the cytosolic proteins p47(phox) and p67(phox) and the small GTPase Rac (1 or 2). We proposed that Rac1 serves as a membrane-targeting molecule for p67(phox). This hypothesis was tested ... More
A novel function for Cyclin A2: control of cell invasion via RhoA signaling.
Authors:Arsic N, Bendris N, Peter M, Begon-Pescia C, Rebouissou C, Gadéa G, Bouquier N, Bibeau F, Lemmers B, Blanchard JM,
Journal:J Cell Biol
PubMed ID:22232705
'Cyclin A2 plays a key role in cell cycle regulation. It is essential in embryonic cells and in the hematopoietic lineage yet dispensable in fibroblasts. In this paper, we demonstrate that Cyclin A2-depleted cells display a cortical distribution of actin filaments and increased migration. These defects are rescued by restoration ... More
Low affinity interactions of GDPbetaS and ribose- or phosphoryl-substituted GTP analogues with the heterotrimeric G protein, transducin.
Authors:Zera EM, Molloy DP, Angleson JK, Lamture JB, Wensel TG, Malinski JA
Journal:J Biol Chem
PubMed ID:8662741
'We have examined the effects of three commonly used classes of guanine nucleotide analogues on the retinal G protein, transducin (Gt), and found them to be quite different from those that might be expected from results with other GTP-binding proteins. The most surprising results were with guanosine 5''-O-(2-thiodiphosphate) (GDPbetaS); rather ... More
Alanine scan mutagenesis of the switch I domain of the Caulobacter crescentus CgtA protein reveals critical amino acids required for in vivo function.
Authors:Lin B, Skidmore JM, Bhatt A, Pfeffer SM, Pawloski L, Maddock JR
Journal:Mol Microbiol
PubMed ID:11251813
'The Caulobacter crescentus CgtA protein is a member of the Obg/GTP1 subfamily of monomeric GTP-binding proteins. In vitro, CgtA displays moderate affinity for both GDP and GTP and displays rapid exchange rate constants for either nucleotide, indicating that the guanine nucleotide-binding and exchange properties of CgtA are different from those ... More
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