A calcium-induced calcium influx factor, nitric oxide, modulates the refilling of calcium stores in astrocytes.
AuthorsLi N, Sul JY, Haydon PG
JournalJ Neurosci
PubMed ID14614089
The roles of nitric oxide are primarily undefined in astrocytes, cells that are active partners in synaptic transmission. Because nitric oxide synthases are present in astrocytes, we imaged the formation of nitric oxide in cultured murine cortical astrocytes using DAF-FM (4-amino-5-methylamino-2',7'-difluorofluorescein diacetate). We demonstrated that physiological concentrations of ATP induced ... More