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TRA-1-60 Monoclonal Antibody (TRA-1-60), DyLight™ 488
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FIGURE: 1 / 10
TRA-1-60 Antibody (MA1-023-D488X) in ICC/IF
Imunofluorescent analysis of TRA-1-60 (green) in human episomal iPSC cells. Cells were grown on vitronectin coated plates, fixed with 4% paraformaldehyde for 15 minutes, and blocked with 3% Blocker BSA (Product # 37525) for 30 minutes at room temperature. Cells were stained with DyLight 488-conjugated TRA-1-60 monoclonal antibody (left panels, Product # MA1-023-D488X) or DyLight 488-conjugated Mouse IgM isotype control antibody (top right panel, Product # MA1-194-D488), at a dilution of 1:250 and incubated for 1 hour at room temperature. N... View More
Product Details
MA1-023-D488X
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
TRA-1-60
Immunogen
Human embryonal carcinoma cell line 2102Ep
Conjugate
DyLight™ 488
DyLight™ 488
DyLight™ 488
Excitation/Emission Max
492/519 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Affinity chromatography - MBP
Storage buffer
PBS with 1mg/mL BSA
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-023-D488X has successfully been used in immunofluorescence assays with human samples.
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GCTM-2 antigen; Gp200; MGC138240; PC; PCLP antibody; PCLP1 antibody; PODLX2; Podocalyxin; Podocalyxin-like protein 1; podolyxin; unnamed protein product
Gene Aliases: gp135; Gp200; PC; PCLP; PCLP-1; PCLP1; PDX; PODXL; PODXL1
UniProt ID: (Human) O00592
Entrez Gene ID: (Human) 5420
cell adhesion
negative regulation of cell adhesion
cell migration
regulation of cell-cell adhesion
negative regulation of cell-cell adhesion
positive regulation of cell migration
regulation of microvillus assembly
positive regulation of cell-cell adhesion mediated by integrin
glomerular visceral epithelial cell development
epithelial tube formation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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