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Invitrogen
Hepatitis C Virus Core Antigen Monoclonal Antibody (C7-50)
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产品信息
MA1-080
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
已发表种属
C. elegans,
Virus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
C7-50
抗原
Purified HCV core-GST fusion protein (genotype 1b).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-080 detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
MA1-080 has been successfully used in Western blot, immunoprecipitation, immunofluorescence and ELISA procedures. By Western blot, this antibody detects a single ~21 kDa protein representing HCV core protein in various transfected cell lines. Immunofluorescence staining of HCV core protein in transfected chimp hepatocytes yields a staining pattern consistent with cytoplasmic and vesicular staining.
The MA1-080 immunogen is purified HCV core-GST fusion protein (genotype 1b). This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.
靶标信息
HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
